低水平爆炸暴露对军事人员认知功能的累积和上下文影响:与PTSD和轻度TBI的相互作用
Sarah L Martindale1, Jason M Bailie, Shannon R Miles
1Author Affiliations: Research & Academic Affairs Service Line, Salisbury VA Healthcare System, Salisbury, NC (Dr Martindale, Dr Magnante,Ms Craig, Dr Rowland); Department of Translational Neuroscience (Drs Martindale, Rowland) and Department of Neurology (Dr Magnante), Wake Forest School of Medicine, Winston-Salem, NC; Traumatic Brain Injury Center of Excellence, Silver Spring, MD (Drs Bailie, Babakhanyan); Naval Hospital Camp Pendleton, Camp Pendleton, CA (Drs Bailie, Babakhanyan); General Dynamics Information Technology, Fairfax, VA (Drs Bailie, Babakhanyan); James A. Haley Veterans' Hospital, Tampa, FL (Dr Miles); Psychiatry & Behavioral Neurosciences, University of South Florida, Tampa, FL (Dr Miles); Department of Physical Medicine and Rehabilitation, School of Medicine, Virginia Commonwealth University, Richmond, VA (Dr Walker); Richmond Veterans Affairs Medical Center, Central Virginia VA Health Care System, Richmond, VA (Dr Walker); Research, Minneapolis VA Health Care System, Minneapolis, MN (Dr Davenport); Department of Psychiatry and Behavioral Health, University of Minnesota, Minneapolis, MN (Dr Davenport); and Uniformed Services University, Bethesda, MD (Col Dr Hinds).Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's website ( www.headtraumarehab.com ).
低水平雷射 (LLB) 暴露并没有直接损害认知功能. 然而,LLB与创伤后应激障碍 (PTSD) 和轻度创伤性脑损伤 (TBI) 相互作用,影响了服务人员和退伍军人的认知表现.
科学领域:
- 神经科学是一个神经科学.
- 军事医学 军事医学
- 认知心理学 认知心理学
背景情况:
- 战斗暴露的服务人员和退伍军人 (SM/Vs) 经常经历低水平爆炸 (LLB) 暴露.
- 对LLB对认知功能的影响,特别是与创伤后应激障碍 (PTSD) 和轻度创伤性脑损伤 (TBI) 相结合,需要进一步调查.
研究的目的:
- 研究LLB暴露对SM/Vs认知表现的影响.
- 检查PTSD和部署相关的TBI在LLB和认知结果之间的关系中的缓解作用.
主要方法:
- 对1036个SM/V进行了横截面的观察性研究.
- 数据从多个地点的国防部和退伍军人事务研究中心收集.
- 用标准化措施和神经心理测试评估认知功能,LLB暴露,PTSD和TBI.
主要成果:
- 对LLB的暴露并没有独立地与认知缺陷有关.
- 对LLB的暴露缓解了PTSD和视觉记忆之间的关联.
- 创伤后应激障碍和创伤后创伤之间的相互作用显著影响了口头记忆,工作记忆和处理速度.
结论:
- 虽然单独LLB不会导致认知缺陷,但它与PTSD和TBI的相互作用至关重要.
- 对爆炸暴露,PTSD和TBI的综合评估对于评估SM/Vs的认知健康至关重要.
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