相关实验视频

Updated: Jan 17, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Published on: July 11, 2016

阿克罗巴克特物种的临床和微生物学特征:一个10年的多中心实验

David R Bayless¹, Mitchell G Dumais¹, Jack W McHugh²

¹Department of Internal Medicine, Mayo Clinic College of Medicine & Science, Rochester, Minnesota, USA.

Journal of clinical microbiology

|September 19, 2025

概括

阿克罗巴克特菌感染很少见,通常影响免疫力低下的人. 用皮佩拉西林 - 塔扎巴克坦,卡巴烯姆或三甲 - 硫甲醇的初始治疗得到了敏感性数据的支持.

科学领域:

微生物学微生物学
传染性疾病传染性疾病
临床医学临床医学

背景情况:

阿克罗巴克特菌种是格兰氏阴性细菌,在免疫功能低下的人和患有囊性纤维化的人中引起感染.
有限的临床和微生物学数据存在于Achromobacter感染,阻碍最佳的治疗策略.

研究的目的:

在10年的时间内分析Achromobacter分离物的临床和微生物学特征.
评估抗微生物敏感性模式,以指导治疗决策.

主要方法:

从2013-2023年对1598个Achromobacter分离物 (血液流和非血液流) 在三个梅奥诊所的位置进行了回顾性分析.
对阿克罗巴克特菌血流感染的成年患者的临床数据的检查.

主要成果:

最常见的物种是Achromobacter xylosoxidans,这是最常见的物种. 血液感染发生在老年,免疫力低下的患者中,这些患者有中央静脉导管.
在血液中分离的血流中观察到对美罗烯姆,皮佩拉林-塔扎巴克坦和三甲胺-硫甲醇的高度敏感性 (> 90%).
呼吸道是非血流隔离物的主要来源,对几种抗生素具有很高的敏感性,但对诺基诺和氨基甘油酸具有耐药性.

结论:

推使用皮佩拉西林-塔扎巴克坦,卡巴恩或三甲-硫法索作为Achromobacter感染的初始治疗方法.
进一步的研究是必要的,以充分阐明阿克罗姆巴克特感染的临床和微生物学的方面.

关键词:

这种细菌是Achromobacter.亚克罗巴克特菌血流感染亚克罗巴克特克西洛索克西丹斯 (Achromobacter xylosoxidans) 是一种植物.多中心研究多中心研究.在非血流中的Achromobacter分离物.

更多相关视频

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing

Characterization of a Pathogenic Escherichia coli Strain Derived from Oreochromis spp. Farms Using Whole-Genome Sequencing

Published on: December 23, 2022

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

Published on: April 19, 2024

相关概念视频

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

Bacterial Phylum Actinobacteria

Bacterial Phylum Actinobacteria

Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...