使用可注射的富血小板纤维素来改善受冲击的第三下部提取后的恢复:一项随机对照临床试验
Angelo Aliberti1, Mauro Mariniello1, Marco Bergaminelli2
1Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Via Sergio Pansini 5, Naples, 80131, Italy.
Clinical oral investigations
|September 19, 2025
概括
可注射的富含血小板纤维素 (i-PRF) 在受冲击的第三下部提取后显著减少胀和疼痛. 这种治疗还可以加速外科创伤愈合,改善患者的早期术后结果.
科学领域:
- 口腔和牙面部外科手术
- 再生医学是一种再生医学.
- 伤口治愈研究研究 伤口治愈研究
背景情况:
- 受冲击的第三下部提取是常见的外科手术手术.
- 手术后的并发症包括胀,疼痛和伤口愈合的延迟.
- 富含血小板纤维素 (PRF) 是一种具有潜在再生特性的自身生物材料.
研究的目的:
- 临床评估可注射血小板丰富纤维素 (i-PRF) 在经受影响的第三下部提取后管理术后结果的疗效.
- 评估i-PRF对胀,疼痛和伤口愈合的影响.
- 为了比较i-PRF治疗与自发口愈合.
主要方法:
- 一个双盲,并行组,随机对照的临床试验与56名患者进行.
- 患者被分为对照组 (自发愈合) 和试验组 (i-PRF 粘膜下透).
- 在特定的术后间隔测量胀,疼痛 (VAS尺度) 和伤口愈合 (愈合指数).
主要成果:
- 与对照组相比,i-PRF组在第3天和第7天显示出胀的统计显著减少.
- 在第1天和第3天 (p < 0.001) 观察到i-PRF组显著减少疼痛 (p < 0.001).
- 在所有测量时间点 (p <0.05) 中,i-PRF组的外科创伤愈合显著改善.
结论:
- 粘膜下i-PRF透有效减少手术后的胀和疼痛后受影响的第三下部提取.
- i-PRF促进了手术伤口愈合的加速,促进了早期的恢复.
- i-PRF提供一种最小侵入性的自主选择,以提高患者的舒适性并缩短恢复时间.
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