近视儿童眼内压力趋势 接受氨酸治疗的近视儿童
Yun Hsia1,2, Pao-Ju Chen1, I-Hsin Ma1,2
1Department of Ophthalmology, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu, Taiwan.
Ophthalmology and therapy
|September 19, 2025
概括
针对儿童近视控制的局部类药物显示,在18个月内,眼内压力 (IOP) 略有增加. 然而,这种近视治疗没有显著影响视网膜神经纤维层厚度.
科学领域:
- 眼科医生 眼科 眼科
- 儿科眼科医生 儿科眼科医生
- 眼睛近视管理 管理近视
背景情况:
- 局部氨酸是一种常见的治疗方法,用于减缓儿童近视的进展.
- 有关其对眼内压力 (IOP) 的长期影响存在担忧.
研究的目的:
- 为了评估局部阿特罗宾在儿科近视患者的IOP上的纵向影响.
- 评估氨酸对视网膜神经纤维层 (RNFL) 和质细胞复合体 (GCC) 厚度的影响.
主要方法:
- 追溯纵向研究,比较使用0.125%氨酸的儿童与非使用者.
- 重复的IOP测量和光学连贯性断层扫描 (OCT) 用于RNFL和GCC厚度.
- 多变量多级模型根据相关的共变量进行调整.
主要成果:
- 氨酸组经历了统计学上显著的,但适度的,平均每年增加0.51 mmHg的内血压.
- 在阿特罗平和对照组之间没有观察到RNFL或GCC厚度的显著差异.
- 与对照组相比,氨酸组的最终内血压较高 (18.3 mmHg与16.7 mmHg).
结论:
- 用于小儿近视控制的局部阿特罗宾的使用与IOP的小幅增加有关.
- 这种IOP增加似乎没有对RNFL厚度产生负面影响.
- 建议对接受近视治疗的儿童进行定期的IOP监测.
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