关于前列腺癌的生殖线检测的男性患者报告的结果:来自 PROGRESS 注册表的结果
Stacy Loeb1, Scott W Keith2,3, Laura Gross4
1Department of Urology and Population Health, New York University Langone Health and Manhattan Veterans Affairs, New York, NY.
JCO precision oncology
|September 19, 2025
概括
来自PROGRESS注册表的患者报告结果 (PROs) 显示,前列腺癌 (PCA) 生殖线检测 (GT) 的满意度在电话咨询中最高. 了解这些PRO可以改善PCA遗传测试的患者体验.
科学领域:
- 在瘤学瘤学.
- 遗传学 遗传学 是一个
- 患者报告的结果
背景情况:
- 前列腺癌 (PCA) 的生殖线检测 (GT) 对于精确治疗,癌症查和评估遗传风险至关重要.
- 研究患者报告结果 (PROs) 对于开发以患者为中心的PCA GT策略至关重要.
研究的目的:
- 分析来自PROGRESS注册表的患者报告结果 (PROs) 在接受PCA生殖基因测试 (GT) 的男性中.
- 确定影响患者满意度,决策冲突和PCA GT.感知效益的因素.
主要方法:
- 通过在线调查,PROGRESS注册表收集了18岁以上的英语男性的数据,他们以前/目前有PCA GT.
- 数据包括人口统计,PCA和家族癌症史,遗传护理提供,满意度,决策冲突,知识和态度.
- 多重线性回归被用来分析参与者特征和PROs (α = .05) 之间的关系.
主要成果:
- 分析包括414名参与者;27.9%的人有积极的遗传结果.
- 最高的满意度与通过电话或与医生讨论的预测咨询有关.
- 具有突变的男性报告GT的感知效益和重要性更高;亚裔美国人报告满意度更低,决策冲突更高.
结论:
- PROGRESS注册表提供了第一个关于男性经历PCA GT的PROs的全面报告.
- 结果提供了改善患者体验和最大限度地提高PCA生殖基因检测的好处的见解.
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