人类小脑和社会导航:使用动态因果建模的小脑-大脑连接
Meijia Li1,2, Min Pu3, Kris Baetens1
1Faculty of Psychology and Center for Neuroscience, Vrije Universiteit Brussel, Brussels, 1050, Belgium.
Social cognitive and affective neuroscience
|September 19, 2025
概括
这项研究揭示了小脑和参与社会认知的大脑区域之间的双向联系,这对社会导航至关重要. 大脑小道适应违反社会规范的情况,增强我们对社会行为调节的理解.
科学领域:
- 神经科学是一个神经科学.
- 社会认知神经科学 社会认知神经科学
背景情况:
- 社交导航依赖于在复杂环境中的目标和偏好.
- 小脑后部对于社会行为和导航至关重要,但其大脑-大脑通路研究不足.
研究的目的:
- 研究大脑大脑通路在社会导航中的作用.
- 检查小脑和皮层思维区域之间的连接在社会导航过程中如何变化,特别是对违反社会规范的反应.
主要方法:
- 在四项社会导航研究 (N=107) 的数据上使用动态因果建模 (DCM).
- 分析了小脑Crus 2和皮质区域 (尾结,前,中部前额叶皮层) 之间的功能连接.
- 基于主动与被动观察以及社会与非社会序列的调制.
主要成果:
- 鉴定了大脑小细胞Crus 2和关键的精神化区域 (顶交点,前皮质,中部前额叶皮质) 之间的广泛的双向连接,无论是斜侧还是斜侧.
- 通过主动编码或社交与非社交环境观察到连接的最小调制.
- 在违反社会规范时发现了连接的显著变化:右Crus 2增加到腹部中部前额叶皮层 (mPFC) 和precuneus到左Crus 2连接,以及左Crus 2到腹部mPFC连接减少.
结论:
- 小脑通过大脑-大脑路径在社会导航和行为调节中发挥着重要作用.
- 连接模式在应对违反社会规范时动态调整,突出显示小脑在社会认知中的适应性功能.
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