睡眠架构和REM睡眠没有阿托尼亚在后COVID-19失眠失眠
Abubaker Ibrahim1, Matteo Cesari1, Qi Tang1
1Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.
Sleep
|September 19, 2025
概括
后COVID-19失眠显示出明显的多睡眠学发现,包括增加REM睡眠没有动 (RWA) 和改变睡眠完整性,表明生理变化超出了大流行压力. 这些睡眠变化可能表明病毒感染中枢神经系统.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 传染性疾病 传染性疾病
背景情况:
- 失眠是COVID-19感染的常见后果,特别是在长期COVID患者中.
- 以前的研究主要使用问卷来评估COVID-19后的睡眠障碍.
- 多睡眠学 (PSG) 尚未得到广泛的应用,以确定这一群体的客观睡眠发现.
研究的目的:
- 在COVID-19后失眠患者中调查独特的多睡眠图 (PSG) 发现.
- 为了比较后COVID-19失眠,大流行时代非COVID失眠和大流行前慢性失眠组之间的PSG数据.
主要方法:
- 一项研究包括150名患有慢性失眠的患者,分为三组 (每组n=50):COVID-19后的失眠,大流行时期的非COVID失眠和大流行前的慢性失眠.
- 所有参与者都接受了一晚的视频多梦摄影 (v-PSG).
- 分析了睡眠架构,呼吸变量和没有动的REM睡眠 (RWA),并将其与不同组进行了比较.
主要成果:
- 两组之间标准PSG变量 (总睡眠时间,睡眠效率,睡眠阶段,呼吸暂停-呼吸暂停指数) 没有发现显著差异.
- 在COVID-19后的失眠患者表现出显著增加的RWA (下巴和flexor digitorum superficialis) 和更高的夜间心率.
- 睡眠分析显示,在COVID-19后的失眠组中,N3睡眠周期较短,REM睡眠持续时间较长,N3连续性下降的趋势.
结论:
- COVID-19后失眠的经典PSG概况与非COVID相关的慢性失眠相似.
- 微妙的PSG差异,包括RWA升高和睡眠完整性改变,表明生理变化可能与病毒中枢神经系统 (CNS) 参与COVID-19后失眠有关.
- 这些发现表明,COVID-19后的失眠可能源于超出一般流行病相关压力的因素.
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