红色体数和从怀孕早期开始的母亲的循环适应:鹿特丹周孕队列 (预测研究)
L W Voskamp1,2, J J Koerts1, R E Wiegel1
1Department of Obstetrics & Gynaecology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Human reproduction (Oxford, England)
|September 19, 2025
概括
没有黄体 (CL) 的怀孕显示出更高的平均动脉压和下子宫动脉脉动力和抵抗指数. 这些发现表明,根据目前的CL数量,母亲的循环适应发生了变化.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 怀孕期间的心血管生理学
背景情况:
- 不同的受孕方法产生不同的黄体体 (CL) 数量,影响怀孕结果.
- 之前的研究指出,基于CL计数,高血压疾病和出生体重存在差异.
- 改变母亲的心血管适应与CL的存在或缺乏有关,可能是由于荷尔蒙因素.
研究的目的:
- 调查红色体 (CL) 数量与母亲的循环适应之间的关联.
- 评估CL计数与血压和子宫动脉多普勒指数之间的关系.
主要方法:
- 对1986名单独怀孕的女性 (2010-2022) 的前性研究.
- 根据怀孕方法将怀孕分为0,1或>1CL.
- 使用了经过调整以混因素的线性混合模型,包括平均动脉压和子宫动脉多普勒结果.
主要成果:
- 与1个CL相比,0个CL的女性的平均动脉压显著更高.
- 子宫动脉脉动率指数 (PI) 和抵抗指数 (RI) 在0个临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床
- 怀孕>1CL显示出与1CL组相似的子宫动脉指数,除了22周稍高一些的RI.
结论:
- 黄体缺失与平均动脉压升高和子宫动脉血管阻力降低有关.
- 这些循环适应可能导致在没有CL的怀孕中高血压疾病的发病率更高.
- 这些发现支持优化ART策略,以改善母亲和新生儿的结果.
关键词:
关于ICSI的结果在这个过程中,IVF IVF.辅助生殖 辅助生殖是一种辅助生殖.血压 血压 血压 血压循环循环的循环循环.黄体体 (Corpus luteum) 是一个体.平均动脉压力是指动脉的压力.子宫动脉脉动率指数是什么子宫动脉阻力指数更多相关视频
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