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Updated: Jan 17, 2026

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介素-10限制了慢性亚临床等离子体感染中免疫介导的病理

Leandro de Souza Silva1, Brian G Monks1, Catherine S Forconi1

  • 1Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, United States of America.

PLoS neglected tropical diseases
|September 19, 2025
PubMed
概括

来自CD4+T细胞的互白素-10 (IL-10) 在慢性亚临床菌感染期间预防严重炎症. 在小鼠中阻断IL-10信号导致致命的炎症反应,突出IL-10信号.

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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