由自然衍生化合物对乳酸脱酶四聚化进行基于机制的向:对分子对接,分子动力学和QSAR分析的调查

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Shiva Farmani1, Najme Dehghanbanadaki2, Mahan Balooei3

  • 1Department of Biology, Faculty of Science, Yazd University, P.O. Box 8915818411, Yazd, Iran; Zista_Academy Technology Core, Science and Technology Park, Tarbiat Modares University, P.O. Box: 14115111, Tehran, Iran.

Computers in biology and medicine
|September 19, 2025
PubMed
概括

研究人员确定了通过向乳酸脱酶 (LDH) 四聚化来抑制癌症的天然化合物. 这些化合物,如普尼卡福林和Myricetin galloyl-hexoxide,通过稳定非原生LDH二分体构造来破坏癌细胞代谢.

关键词:
癌症 癌症 癌症 癌症计算机辅助药物设计乳酸脱酶的使用方法医疗植物 医疗植物代谢重编程是一种代谢重编程.

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