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联合UGT2B17和GSTA1基因型对埃克塞梅斯坦药物遗传学的影响

Shaman Luo1, Julia Trudeau2, Vikki Ho3

  • 1Division of Molecular Biosciences, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo (SUNY), Buffalo, New York; Department of Pharmaceutical Sciences, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington.

Drug metabolism and disposition: the biological fate of chemicals
|September 19, 2025
PubMed
概括

在UGT2B17和GSTA1中的遗传变异会影响身体如何处理乳腺癌药物埃克塞梅斯坦 (EXE),这是一个重要的乳腺癌药物. 了解这些遗传差异可以帮助预测患者对EXE治疗的反应.

关键词:
这里是Exemestane.在GSTA1上,它是GSTA1.基因型 基因型 基因型代谢过程中的代谢.美国UGT2B17

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