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Gokberk Unal1, Yu-Qing Xie1, Martin Fussenegger2

  • 1Department of Biosystems Science and Engineering, Eidgenössische Technische Hochschule Zurich, Schanzenstrasse 48, 4056 Basel, Switzerland.

Cell metabolism
|September 19, 2025
PubMed
概括

一个新的遗传电路,CHARM,有效地感知并实时调节高胆固醇水平. 这种工程系统恢复了高胆固醇贫血小鼠的胆固醇稳态,为治疗失脂症提供了新的治疗策略.

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