关键先天性心脏缺陷检测的时间:一个多站点基于人口的研究
Shannon E Moss1, Elizabeth C Ailes1, Karrie F Downing1
1Division of Birth Defects and Infant Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA.
The Journal of pediatrics
|September 19, 2025
概括
临界先天性心脏缺陷 (CCHD) 的产前检测增加,但晚期检测仍然是一个问题,特别是对于没有保险的母亲来说. 早期诊断CCHD对于婴儿健康结果至关重要.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 公共卫生 公共卫生
- 医学诊断 医学诊断 医学诊断
背景情况:
- 严重先天性心脏缺陷 (CCHD) 是婴儿死亡率和发病率的重要原因.
- 早期发现CCHD对于及时干预和改善结果至关重要.
- 检测时间的变化,包括产前,产后及时和产后晚期,影响管理策略.
研究的目的:
- 确定产前和晚期CCHD检测的流行率和趋势.
- 为了确定与产前和晚期CCHD检测相关的人口和临床因素.
- 了解CCHD检测时间的差异.
主要方法:
- 从出生缺陷研究评估怀孕暴露S (2014-2021) 中分析患有心血管疾病的婴儿.
- CCHD检测时间的分类:产前,及时产后 (0-3天) 和晚 (>3天).
- 统计建模 (日志线性和日志二项式) 来评估趋势和流行率.
主要成果:
- 在产前发现CCHD的比例从2014年的25.0%上升到2021年的39.1%.
- 晚期CCHD检测的流行率略有下降,但仍然显著 (2014年为22.7%,2021年为16.4%).
- 患有心脏外缺陷的婴儿有更高的产前检测率;晚期检测在没有保险的母亲的婴儿中更为常见.
结论:
- 根据缺陷特征和母亲保险状况,CCHD检测时间存在显著差异.
- 需要改进产前检测方法,以识别更广泛的CCHD类型.
- 提高获得产前护理的机会对于减少晚期CCHD检测和改善早期诊断至关重要.
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