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Updated: Jan 17, 2026

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
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皮里米迪尼尔化:对抗癌细胞毒性具有选择性

Rohina Alim1, Scott D Andrew1, Christopher J Parkinson1

  • 1School of Dentistry and Medical Sciences, Charles Sturt University, NSW 2800, Australia.

Bioorganic & medicinal chemistry letters
|September 19, 2025
PubMed
概括

新的pyrimidinyl hydrazones (PH) 通过结合金属和产生活性氧来显示强大的抗癌活性. 这些化合物对各种癌细胞系具有强烈的细胞毒性,对正常细胞的毒性最小,需要进一步研究.

关键词:
细胞毒性 细胞毒性金属复杂的复杂金属.没有NNN 化剂胺基酸 (PH) 是一种酸.这种类型的西米亚巴.

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