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心理社会疼痛管理改善阿片类药物使用障碍治疗结果研究:随机对照试验的协议

Mark Ilgen¹, Frederic Blow¹, John D Piette²

¹Department of Psychiatry, University of Michigan School of Medicine, 2800 Plymouth Road, Building 16, Ann Arbor, MI 48109, USA; Center for Clinical Management Research (CCMR), VA Ann Arbor Healthcare System, 2800 Plymouth Road, Building 16, Ann Arbor, MI 48109, USA.

Contemporary clinical trials

|September 19, 2025

概括

这项研究调查了阿片类药物使用障碍和慢性疼痛患者的心理社会干预. 这些发现将有助于改善这些患者的治疗保留和治疗结果.

科学领域:

临床心理学临床心理学
成药物药物药物药物
疼痛管理疼痛管理

背景情况:

阿片类药物使用障碍 (OUD) 经常与慢性疼痛并发,使治疗复杂化.
布普伦诺芬 (阿片类药物使用障碍药物 - MOUD) 是OUD的标准护理,有助于缓解疼痛,但治疗的保留是一个挑战.
对OUD和慢性疼痛的综合方法研究不足.

研究的目的:

评估心理社会疼痛管理干预 (PPMI) 是否改善慢性疼痛患者的MOUD保留.
与增强常规护理 (EUC) 相比,评估远程交付PPMI的有效性.

主要方法:

一项随机试验 (持续研究) 涉及200名成年人接受MOUD治疗OUD并经历慢性疼痛.
参与者被随机分配到PPMI (8次会议) 或EUC (2次会议) 在6周内.
主要结局:在3个月内保留布普伦诺芬;次要结局:在12个月后保留MOUD,疼痛,功能和物质使用.

主要成果:

这项研究评估了远程交付,手动化心理社会干预的影响.
结果将指导策略,以提高治疗保留和结果.
该试验已在临床试验.gov (ID:NCT04433975) 上注册.

结论:

在OUD患者和在布普伦诺芬中同时出现的慢性疼痛患者中测试了一种远程交付的心理社会干预措施.
这些发现旨在为患有慢性疼痛的MOUD患者提供改善的保留和结果.
这项研究解决了对综合护理模式的关键需求.

关键词:

慢性疼痛是一种慢性疼痛.认知行为疗法是一种认知行为疗法.治疗阿片类药物使用障碍的药物.对阿片类药物的依赖.药物使用障碍药物使用障碍

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