Brg1-打印的染色质状态控制效应和记忆组2先天性淋巴细胞代谢以加剧过敏性肺炎

Jupei Tang1, Hanxiao Sun2, Huidan Chang3

  • 1Shanghai Institute of Nutrition and Health, University of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.

概括

染色体重塑剂Brg1通过促进2组先天性淋巴细胞 (ILC2) 扩张和糖解,驱动过敏性肺炎. 抑制 Brg1 缓解炎症,提供了一个潜在的治疗点.

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