担心跌倒的老年人中压力系统和炎症之间的关系 - - FEARFALL研究的发现
Anja Müller1, Robert Kob2, Cornel Christian Sieber3
1Department of Psychology, Health Psychology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Nägelsbachstrasse 49a, Erlangen, Bavaria, 91058, Germany.
Experimental gerontology
|September 19, 2025
概括
老年人对跌倒 (CaF) 的担忧与压力系统活动有关. 对跌倒的更高感知控制与皮质醇水平相关,这表明心理因素影响了老年人的压力调节.
科学领域:
- 老年学是一门学科.
- 心理神经内分泌学心理学
- 压力生理学 压力生理学
背景情况:
- 对跌倒 (CaF) 的担忧会对老年人的活动和健康产生负面影响.
- 了解CaF,压力和炎症之间的相互作用对于老年人的健康至关重要.
研究的目的:
- 调查CaF,压力系统活性 (皮质醇,α-氨基酶) 和社区居住的老年人中低度炎症 (CRP,IL-6) 之间的关联.
- 探索心理因素,特别是对跌倒的感知控制在调节这些生理反应中的作用.
主要方法:
- 该FEARFALL研究招募了160名老年人 (≥70岁),分析了102人的数据.
- 使用国际落效率尺度 (FES-I),FES-I避免行为 (FES-IAB) 和更新的落控制感知尺度 (UP-CoF) 评估了CaF.
- 唾液样本测量了皮质醇和α-氨基酶;血液样本测定了C-反应蛋白 (CRP) 和中白素-6 (IL-6).
主要成果:
- 较高的UP-CoF得分与较高的个人皮质醇值 (p=0.047) 有显著的关联,并且与较快的白天皮质醇下降 (p=0.059) 有边际的关联.
- 在CaF测量和α-amylase之间没有发现显著的关联.
- 在CaF和炎症标志物 (CRP,IL-6) 之间没有观察到显著的关联,尽管IL-6和CRP与年龄和BMI有关.
结论:
- 对跌倒的感知控制与老年人的生理皮质醇动态有关.
- 心理因素,如感知控制,可能在调节老年人压力系统活动方面发挥作用.
- 需要进一步的研究来阐明心理健康,压力生理学和老年人跌倒预防之间的复杂关系.
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