脊椎动物皮肤末端器官复合物的发展
José A Vega1, Yolanda García-Mesa2, Patricia Cuendias2
1Departamento de Morfología y Biología Celular, Grupo SINPOS, Universidad de Oviedo, Oviedo, Spain; Facultad de Ciencias de la Salud, Universidad Autónoma de Chile, Providencia-, Santiago, Chile.
脊椎动物的皮肤含有感觉体,可以将触摸转化为电信号. 本综述详细介绍了哺乳动物和鸟类中这些机械传感器的发育和细胞组成部分.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 历史学 历史学 历史学
背景情况:
- 无毛皮肤中的皮肤末端器官复合体将物理刺激转化为神经信号.
- 这些机械传感器包括轴突,质细胞和结缔组织外.
- 这些组成部分的变化形成了不同的感官体细胞类型,如Meissner,Pacini,Ruffini,Grandry和Herbst体细胞.
研究的目的:
- 提供关于皮肤感官体细胞的发展的最新评论.
- 阐明细胞和分子机制背后的机制传感器的形成.
- 为了比较不同物种的体细胞发育,包括鸟类,动物和人类.
主要方法:
- 审查关于感官体细胞发育的现有文献.
- 分析神经和介质细胞组成部分之间的细胞相互作用.
- 检查鸟类,动物和人类系统中的分子调节.
主要成果:
- 皮肤末端器官复合体通过Aβ-轴突,终端质细胞和周围介质体之间的复杂相互作用而发展.
- 参与体质细胞形成的神经和质细胞都来自神经.
- 确定了控制这些发育过程的特定分子机制.
结论:
- 多种机械传感器形态型的发展是由复杂的细胞交叉声调节的.
- 了解这些发育途径为感官受体生物学提供了洞察力.
- 本综述综合了有关脊椎动物触摸受体形成的当前知识.
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