内源性T细胞格局被CAR-T细胞疗法重塑,并预测多发性骨髓瘤的治疗反应

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Julia Frede1,2,3,4, Julia C Poller5,6,7, Kayleen Shi5,8,7

  • 1Department of Medical Oncology, Jerome Lipper Multiple Myeloma Center, Dana Farber Cancer Institute, Boston, MA, USA. julia.frede@tum.de.

Leukemia
|September 19, 2025
PubMed
概括

卡尔-T细胞疗法改变了T细胞格局,导致了与骨髓瘤患者的不良结果相关的新型细胞群. 向TIM3/GAL9可能会改善T细胞的持久性和免疫治疗的有效性.

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