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Baltaj S Sandhur1, Mohit Jethi2, Natasha Gautam2,3
1Department of Ophthalmology, Jacobs School of Medicine and Biomedical Sciences, Buffalo, United States. baltajsa@buffalo.edu.
Lasers in medical science
|September 20, 2025
概括
慢凝血连续波循环光凝血 (SC-CWCPC) 在MicroPulse跨质循环光凝血 (MP-TSCPC) 失败后有效治疗耐火玻璃眼. 这种安全的干预措施显著降低了青光眼患者的眼内压力和药物使用.
科学领域:
- 眼科医生 眼科 眼科
- 青光眼治疗方法 青光眼治疗方法
- 手术干预 手术干预
背景情况:
- 耐火性玻璃眼是一个挑战,通常需要多次干预.
- 微脉冲跨细胞循环光凝血 (MP-TSCPC) 是一种治疗选择,但其失败需要使用其他策略.
- 在MP-TSCPC失效后,慢凝血连续波环光凝血 (SC-CWCPC) 的疗效尚未得到充分证实.
研究的目的:
- 评估SC-CWCPC在失控眼内压 (IOP) 患者的疗效和安全性,其结果是MP-TSCPC程序失败.
- 为了确定SC-CWCPC在治疗耐火玻璃眼的成功率.
- 评估SC-CWCPC对MP-TSCPC失败后IOP和药物要求的影响.
主要方法:
- 在MP-TSCPC失败后接受SC-CWCPC的患者的回顾性病例系列.
- 在2022年1月至2024年10月期间由单个青光眼外科医生进行的手术.
- 通过IOP定义的手术成功在6-21mmHg之间,≥20%的IOP降低,没有重新手术,并保持光感知视力.
主要成果:
- 包括8名患者 (10只眼睛),平均年龄为43.75岁.
- 在SC-CWCPC (p=0.002) 后,在3.1种药物下,手术前的IOP为26.10 mmHg降至15.80 mmHg (p=0.002).
- 达到了80%的成功率,平均随访时间为10.97个月;没有显著的视力丧失或视力下降.
结论:
- SC-CWCPC 是一种有效和安全的治疗方法,用于那些已经失败了MP-TSCPC的耐火性玻璃眼患者.
- 这种技术扩大了用于管理复杂的玻璃眼病例的手术选择.
- 当其他方法没有成功时,SC-CWCPC为IOP控制提供了一个可行的解决方案.
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