在接受Tecovirimat治疗的患者中,Mpox疾病的临床结果
Ciarra Leocadio1, Elizabeth Garcia1, Maura Lash1
1New York City Department of Health and Mental Hygiene, Queens, NY, USA.
概括
在708名患者中,Tecovirimat治疗mopox进行了评估. 在mopox治疗延迟和住院的种族差异被确定,需要进一步的研究和干预.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 临床研究 临床研究
背景情况:
- 新兴文献详细介绍了接受tecovirimat的mpox患者的临床特征和结果.
- 了解mopox中tecovirimat的使用对于临床管理和公共卫生战略至关重要.
研究的目的:
- 分析mopox患者治疗tecovirimat的临床特征和结果.
- 确定与mpox患者治疗延迟和住院相关的因素.
- 调查MPOX护理中的潜在种族不平等问题.
主要方法:
- 来自纽约市医疗保健系统的非身份化数据的回顾性分析 (2022年5月至12月).
- 包括可能或确定的mopox患者开始tecovirimat.
- 图表抽象收集人口统计和临床数据,检查治疗延迟和住院的因素.
主要成果:
- 708名患者接受了tecovirimat;中位数年龄为36岁,80%是与男性发生性关系的男性,56%是艾滋病毒感染者.
- 罕见的副作用 (14%) 和严重的不良事件 (1%);常见的后果是痕 (10%).
- 14%的患者住院治疗;治疗的中位时间为8天. 与西班牙裔患者相比,非西班牙裔黑人患者面临延迟治疗和住院的风险更高.
结论:
- 确定了tecovirimat启动和住院治疗的常见迹象.
- 在MPOX住院和治疗延迟方面观察到显著的种族不平等.
- 需要进一步的研究和有针对性的干预措施来解决这些差异,并为mopox治疗的临床决策提供信息.
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