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转基因插入的遗传背景可以影响斑马鱼的神经发育

Anna J Moyer1, Jessica A Chrabasz1, Alexia K Barcus1

  • 1Department of Biochemistry and Molecular Biotechnology, The University of Massachusetts Chan Medical School, Worcester, MA 01605, United States.

Genetics
|September 20, 2025
PubMed
概括

斑马鱼Tg(elavl3:KalTA4) 谱系显示了由于Gal4表达和基因插入效应导致的神经发育问题. 研究人员开发了新的神经元促进线,以改善转基因模型的生成.

关键词:
盖德45 盖德45 盖德盖尔4/UAS 系统Tol2 Tol2 Tol2 Tol2 Tol2 Tol2 Tol2 Tol2 Tol2 Tol2 Tol2细胞循环中的细胞循环.神经元发育的神经元发育它们的扩散和扩散.这就是sci-RNA-seqq.转基因的转基因发生.斑马鱼是一种斑马鱼.

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