在一个大型多中心数据库中,更年期前后女性的慢性疼痛患病率和严重程度与男性相比
Adam Ricker1, Nicole Farley1, Jesse J McClure1
1Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA.
Pain management
|September 20, 2025
概括
老年人通常经历的慢性疼痛较少,但51岁及以上的更年期妇女报告的疼痛严重程度比男性更高. 这些发现凸显了针对性疼痛管理策略的需要.
科学领域:
- 疼痛研究 疼痛研究
- 老年学是一门学科.
- 妇女健康 妇女健康
背景情况:
- 慢性疼痛影响了人口的很大一部分.
- 更年期与各种生理变化有关,这些变化可能会影响疼痛感知.
- 了解慢性疼痛中的年龄和性别差异对于有效治疗至关重要.
研究的目的:
- 调查绝经年龄的女性慢性疼痛的患病率和严重程度.
- 为了比较不同年龄和性别的疼痛水平.
- 为了确定慢性疼痛经验的潜在差异.
主要方法:
- 使用NIH赞助的我们所有人的数据库进行观察性研究.
- 包括被诊断患有慢性疼痛的参与者.
- 分类为四个队列:绝经前女性 (18-50岁),绝经后女性 (≥51岁),年轻男性 (18-50岁) 和年长男性 (≥51岁).
- 使用数值评分尺度 (NRS) 评估的疼痛严重程度.
主要成果:
- 总共有53,289名参与者被分析.
- 年龄较大的女性 (≥51) 和年龄较大的男性 (≥51) 报告疼痛水平低于年轻的 (18-50) (p < 0.001).
- 更年期女性 (≥51) 与同龄男性 (≥51) 相比,经历了明显更高的疼痛水平 (p < 0.001).
- 在白人,黑人和非西班牙裔参与者中,研究结果是一致的.
结论:
- 无论性别如何,老年人与年轻人相比,NRS疼痛得分较低.
- 然而,老年女性报告的疼痛严重程度比老年男性更大.
- 这些结果强调需要针对患者量身定制的治疗干预措施,并进一步研究导致疼痛差异的潜在生理和心理社会因素.
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