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Updated: Jan 6, 2026

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功能性DEFB1基因多态性和突hBD-1表达与易受周围假肢关节感染的易感性有关

Yessica Zamudio-Cuevas1, Karina Martínez-Flores1, Ambar López-Macay1

  • 1Laboratorio de Líquido Sinovial, Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra-Ibarra", Mexico City, 14389, Mexico.

Molecular biology reports
|September 20, 2025
PubMed
概括

DEFB1基因的遗传变异通过影响人类β-defensin-1 (hBD-1) 水平,与周围假肢关节感染 (PJI) 风险有关. 交叉体hBD-1可能为PJI病原体提供了洞察力.

关键词:
在 DEFB1 基因中.人类β-防御素-1这是天生的免疫力.周围假肢关节感染单个核酸的多态性.

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