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Updated: Jan 17, 2026

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
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Published on: August 11, 2017

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克服EGFR突变耐药性:在非小细胞肺癌治疗中使用TKI的双抑制策略

Jeevitha Sivam1, Azhar Ariffin1, Ajantha Sinniah2

  • 1Department of Chemistry, Faculty of Science, Universiti Malaya, Malaysia.

European journal of medicinal chemistry
|September 20, 2025
PubMed
概括

双位抑制剂提供了一种有希望的策略,以克服表皮生长因子受体 (EGFR) 突变非小细胞肺癌 (NSCLC) 的耐药性. 通过向多个途径,这些抑制剂提高了疗效,减少了耐药性,从而改善了患者的治疗结果.

关键词:
双重抑制剂 双重抑制剂欧洲农业基金会 (EGFR) 是一个.在NSCLCLC中,我们可以看到NSCLCLC.阻力机制 阻力机制这就是TKI.

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