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计划者间变异性对以知识为基础的治疗规划对中度低分化前列腺癌的影响

Yura Sakuka¹, Motoharu Sasaki², Yuji Nakaguchi³

¹School of Health Sciences, Tokushima University, Tokushima, Japan.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists

|September 20, 2025

概括

这项研究比较了由不同前列腺癌放射治疗规划者创建的RapidPlan模型. 结果显示,规划器变异性影响模型性能,影响目标剂量均性和危险器官节省.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学
医疗保健中的人工智能

背景情况:

快速计划模型越来越多地用于辐射治疗规划.
计划者之间的变化可能会影响治疗计划的质量和一致性.
标准化模型可以提高效率,特别是在资源有限的环境中.

研究的目的:

为了比较不同规划人员开发的RapidPlan模型的性能.
评估计划者之间的变化对前列腺癌治疗计划质量的影响.
评估共享或标准化RapidPlan模型的可行性.

主要方法:

三位规划人员使用30例前列腺癌病例和PlanIQ指导开发了RapidPlan模型.
模型被用来生成12个独立病例的治疗计划.
使用规划目标体积 (PTV-直肠),直肠和膀的剂量-体积参数来评估计划质量.

主要成果:

计划A显示PTV-直肠的剂量均性更好 (较低的D2%,较高的D98%).
计划C实现了最大的直肠节约剂量 (最低V58 Gy).
没有发现统计学上显著的差异,但趋势表明,规划者可变性会影响模型结果.

结论:

规划者的变化可能会影响RapidPlan模型的性能和治疗计划的质量.
模型A在目标剂量的一致性方面表现出色,而模型C提供了优越的风险器官节省.
在模型构造中,质量控制至关重要,标准化模型对放射治疗具有前景.

关键词:

计划计划计划前列腺癌是什么意思前列腺癌是什么意思快速计划快速计划这就是为什么VMAT VMAT.

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