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Updated: Jan 17, 2026

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
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DDX3X可以通过NLRP3 调节痛风炎症 炎症酶激活和巨细胞灭菌 交叉

Linrui Zhong1, Tianyi Lei1, Jianwei Guo2

  • 1Research Center of Hyperuricemia and Gout, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China; Department of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China.

International immunopharmacology
|September 21, 2025
PubMed
概括

死亡盒螺旋酶3X结合 (DDX3X) 通过激活NLRP3炎症体来调节痛风炎症,从而导致巨细胞灭. 这一发现阐明了痛风爆发和缓解的关键机制.

关键词:
这是DDX3XX.这是一种痛风,痛风.在NLRP3炎症酶体中,NLRP3炎症氧化应激是一种氧化应激.热灭菌的发生.

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Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells09:04

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