评估在墨西哥胡阿雷斯市的工作场所的人类乳头瘤病毒自取样计划的试点项目
Svetlana V Doubova1, Saúl Eduardo Contreras-Sánchez1, Sean P McClellan2
1Epidemiology and Health Services Research Unit, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.
Archives of medical research
|September 21, 2025
概括
工作场所人类乳头瘤病毒自取样试点计划 (HPV-SS-PP) 最初增加了宫癌查 (CCS) 覆盖范围,但需要改进,以便在女性工厂工人中更好地参与和跟进. 需要对HPV患病率和查有效性的进一步研究.
科学领域:
- 公共卫生 公共卫生
- 妇科瘤学 妇科瘤学
- 流行病学 流行病学
背景情况:
- 宫癌仍然是一个重要的全球健康问题,特别是在资源较低的环境中.
- 有效的查计划对于早期发现和预防宫癌至关重要.
- 基于工作场所的干预措施可能会改善女性工人的医疗保健机会.
研究的目的:
- 评估工作场所人类乳头瘤病毒自取样试点计划 (HPV-SS-PP) 对宫癌查 (CCS) 覆盖和随访的影响.
- 为了比较HPV自取样的有效性与传统的帕帕尼科劳 (Pap) 涂抹查.
- 评估墨西哥胡阿雷斯市的女性工厂工人中的HPV流行率和随访率.
主要方法:
- 来自墨西哥社会保障研究所 (IMSS) 癌症登记,HPV-SS-PP登记和IMSS附属数据库的数据的二次分析.
- 研究人口:在胡阿雷斯城的35-64岁的IMSS附属工作女性.
- 在HPV-SS-PP实施之前和之后的CCS覆盖率趋势分析,HPV流行率和后续指标.
主要成果:
- HPV-SS-PP实现了44.8%的工厂和42.7%的女性工人参与,最初提高了CCS覆盖率.
- HPV-16/18基因型的流行率为5%,HPV-pool的流行率为18.1%.
- 宫细胞学,结肠镜检查和组织病理学的随访率在HPV阳性女性中为中度至高.
结论:
- HPV-SS-PP显示出潜力,但需要优化,以提高参与度,并确保对阳性HPV结果进行适当的后续调查.
- 该计划与现有医疗保健系统的整合需要进一步改进.
- 持续监测和评估对于改善职业环境中宫癌查策略至关重要.
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