改变pullulan/zein比率对棕托克烯醇乳液电作用的影响
M M Jeevani Osadee Wijekoon1, Abdorreza Mohammadi Nafchi2, Fazilah Ariffin1
1Food Technology Division, School of Industrial Technology, Universiti Sains Malaysia, 11800, Penang, Malaysia.
International journal of biological macromolecules
|September 21, 2025
概括
这项研究使用乳液电来开发快速分解的纳米纤维,以改善托克二醇的输送. 基于pullulan的纳米纤维提高了封装效率,并为功能性食品提供了持续释放.
科学领域:
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
- 食品科学 食品科学 食品科学
背景情况:
- 托克醇 (TRF) 具有强大的抗氧化特性,但由于溶解性低和氧化,其生物利用性差.
- 口服输送系统在有效输送TRF方面面临挑战,限制了它们的治疗和营养潜力.
研究的目的:
- 开发快速分解的纳米纤维,用于封装棕油丰富托克醇分离物 (TRF).
- 为了研究pullulan (P) 和 zein (Z) 比率对纳米纤维特性,TRF加载和释放配置文件的影响.
- 评估这些纳米纤维在功能性食品和营养保健品中增强TRF传递的潜力.
主要方法:
- 使用不同比例的植物性pullulan和 zein聚合物,采用了乳液电.
- 使用扫描电子显微镜 (SEM) 分析了纳米纤维形成,纤维直径和表面形态.
- 评估了封装效率 (EE),负载能力,机械性能和体外药物释放.
主要成果:
- 通过SEM证实了可调节直径 (52.3130.9nm) 的纳米纤维的成功形成.
- 封装效率从71.5%增加到89.0%,TRF负载更高.
- P100:Z0配方表现出最高的EE (86.5%),最佳的机械性能和快速解体 (4秒),同时在180分钟内持续释放TRF.
结论:
- 开发的乳液电纳米纤维有效封装TRF,克服生物可用性限制.
- 该P100:Z0配方提供了一个有前途的系统,用于立即分散和持续释放,增强TRF的交付.
- 这项技术有可能改善功能性食品和营养保健品中托克醇的利用率,特别是对于难以吞的人来说.
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