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从低于最佳状态到超和:低血压手术后的状况通过补充剂来调节
Gabriël Eksteen1, Lia Griner2, Bart Van der Schueren3
1Clinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
The Journal of nutritional biochemistry
|September 21, 2025
概括
服用补充剂的代谢和腹手术 (MBS) 患者具有更高的蛋白P和血水平. 然而,补充剂可能会导致超和水平,因此需要进一步研究最佳剂量.
科学领域:
- 营养生物化学 营养生物化学
- 老年医学 老年医学
- 外科手术的结果
背景情况:
- 代谢和减肥手术 (MBS) 有效治疗肥胖,但存在营养缺乏的风险.
- 目前MBS后的补充指南并没有特别解决,尽管它在预防慢性疾病中的作用.
- 的状态至关重要,因为缺乏和过量摄入都可能是有害的.
研究的目的:
- 为了比较老年人与没有MBS史的Selenoprotein P,血和饮食摄入量.
- 调查补充剂对MBS后个体状态标记物的影响.
- 在这个人群中确定蛋白P水平的预测因子.
主要方法:
- 横截面研究比较了两个组:以前的MBS (BAR) 和对照 (CON),两人都超过65岁.
- 通过使用局部成分数据来评估饮食中的摄入量.
- 测量和分类了蛋白P和血水平;根据补充实践分析了子组.
主要成果:
- 接受MBS并服用补充剂 (BAR-supp) 的参与者与没有补充剂的MBS患者 (BAR-none) 和对照组 (CON-none) 相比,表现出更高的蛋白P和血.
- 在BAR-supp组 (7%) 与BAR-none组 (43%) 之间,亚最佳P蛋白的患病率明显较低.
- 在BAR-supp组中,显著比例 (28%) 的患者表现出超和P蛋白水平,这种状态具有不确定的临床意义.
结论:
- 在MBS后的老年人中补充可以改善状态标志物,但可能导致超和.
- 补充摄入量,食和总体体重减轻被确定为蛋白P水平的预测因素.
- 进一步的研究对于确定最佳补充剂剂量和MBS类型对需求的影响至关重要.
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