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压力,表观遗传改造和FKBP51:通往慢性疼痛脆弱性的途径

Oakley B Morgan1, Samuel Singleton2, Roxana Florea3

  • 1Department of Cell & Developmental Biology, University College London, WC1E 6BT, the United Kingdom of Great Britain and Northern Ireland.

Brain, behavior, and immunity
|September 21, 2025
PubMed
概括

亚慢性压力通过FKBP51增加慢性疼痛易感性,影响表观遗传调节. 在压力期间阻断FkBP51可以减少疼痛的持续性,即使没有逆转Fkbp5低甲基化.

关键词:
慢性疼痛是一种慢性疼痛.通过DNA甲基化.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.Fkbp5p5 在线播放压力 压力 压力 压力脆弱性 易受伤害 脆弱性

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