相关实验视频

Updated: Jan 17, 2026

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
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Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

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Hsp70和Hsp90的翻译后修改和翻译的陪伴者代码.

Sarah J Backe1, Jennifer A Heritz2, Mehdi Mollapour2

  • 1Department of Urology, SUNY Upstate Medical University, Syracuse, NY, 13210, USA; Cancer Center, SUNY Upstate Medical University, Syracuse, NY, 13210.

Cell stress & chaperones
|September 21, 2025
PubMed
概括

像Hsp70和Hsp90这样的分子伴侣体由翻译后修饰 (PTMs) 调节,形成一个"伴侣体代码". 了解这个代码是开发癌症和神经退行等疾病的新疗法的关键.

关键词:
癌症 癌症 癌症 癌症一个共同的主管.热冲击蛋白70 (Hsp70) 是一种热冲击蛋白.热冲击蛋白90 (Hsp90) 是一种热冲击蛋白.分子的伴侣是分子的伴侣.翻译后修改 (PTM) 是一种方法.

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