性别在胸大动脉损伤中的作用
Ilenia D'Alessio1, Nicola Monzio-Compagnoni1, Greta Salinetti2
1Division of Vascular Surgery, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Annals of vascular surgery
|September 21, 2025
概括
性别影响胸大动脉损伤 (BTAI) 的严重程度和治疗结果. 虽然男性遭受的伤害更严重,但接受胸内血管大动脉修复 (TEVAR) 的女性面临更高的并发症风险.
科学领域:
- 创伤外科 手术 创伤外科
- 血管外科 血管外科
- 医学研究 医学研究
背景情况:
- 形胸前动脉损伤 (BTAI) 是多创伤患者死亡的重要原因.
- 五十多岁的男性最常受到BTAI的影响.
- 胸内血管大动脉修复 (TEVAR) 是标准的治疗方法,但性别的影响尚不清楚.
研究的目的:
- 调查BTAI严重程度的性别相关差异.
- 为了确定性别是否影响TEVAR后的术后结果.
主要方法:
- 对大动脉创伤基金会全球注册的回顾性分析.
- 包括623名符合研究标准的患者.
- 使用血管外科学会分类和TEVAR并发症分析评估BTAI严重程度.
主要成果:
- 男人患上更严重的BTAI的可能性更高 (OR 1.500,P=0.035).
- 在384名患者中进行TEVAR.
- 妇女在TEVAR后出现了增加手术前和手术后并发症的趋势,尽管在统计学上并不显著 (P > 0.05).
结论:
- 性别影响BTAI自然史和TEVAR结果.
- 女性患重度BTAI的风险较低,但在TEVAR后似乎会出现更多的并发症.
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