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Updated: Jan 17, 2026

Ion Exchange Chromatography IEX Coupled to Multi-angle Light Scattering MALS for Protein Separation and Characterization
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Ion Exchange Chromatography IEX Coupled to Multi-angle Light Scattering MALS for Protein Separation and Characterization

Published on: April 5, 2019

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离子交换染色学-质谱学的发展,用于完整的蛋白质和蛋白形状的特征

Ziran Zhai1,2, Thomas Holmark1,2, Lars Jasperse1,2

  • 1Analytical Chemistry Group, Van't Hoff Institute for Molecular Sciences (HIMS), University of Amsterdam, Amsterdam, the Netherlands.

Journal of separation science
|September 22, 2025
PubMed
概括

离子交换色谱学与质谱学 (IEC-MS) 相关联,是分析蛋白质电荷异质性和复杂混合物的强大技术. 对于高效的IEC-MS来说,pH梯度方法至关重要,它可以详细描述治疗性蛋白质和变体.

关键词:
收费变种 收费变种完整的蛋白质分析.离子交换色谱学 离子交换色谱学质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量在pH梯度的梯度下,

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Matrix-assisted Laser Desorption/Ionization Time of Flight MALDI-TOF Mass Spectrometric Analysis of Intact Proteins Larger than 100 kDa07:49

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