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Updated: Jan 17, 2026

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KAT6A和PD-L1表达之间的相关性以及KAT6A在结直肠癌中的作用

Zhen-Dong Zhou1, Jian-Pei Zhao1, Shu-Chun Zheng1

  • 1Department of Anal & Intestinal Surgery, Ningbo No. 2 Hospital, Ningbo 315000, Zhejiang Province, China.

World journal of gastrointestinal oncology
|September 22, 2025
PubMed
概括

通过表观遗传激活PD-L1.1,KAT6A驱动着结直肠癌 (CRC) 的进展和免疫逃避. 向KAT6A提供了一种新的策略,以改善CRC患者对免疫检查点抑制剂 (ICI) 的反应.

关键词:
结肠直肠癌是一种癌症.表观遗传调节 表观遗传调节免疫逃逸是一种免疫逃避.在KAT6AA中使用.在PD-L1中.

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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