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Updated: Jan 17, 2026

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与检查点阻塞相结合的不可逆的电穿孔刺激了肝细胞癌小鼠模型中的抗瘤免疫反应

Yan-Li Xing1, Hong-Mei Li1, Xiao-Ming Pang1

  • 1Department of Oncology, Guangzhou Fuda Cancer Hospital, Jinan University, Guangzhou 510655, Guangdong Province, China.

World journal of gastrointestinal oncology
|September 22, 2025
PubMed
概括

结合不可逆的电穿孔 (IRE) 与抗编程细胞死亡蛋白1 (PD-1) 疗法,可以增强抗瘤免疫力,并在肝细胞癌模型中显著降低瘤体积. 这种协同方法为癌症切除和免疫治疗提供了一个有希望的新策略.

关键词:
抗癌免疫力 抗癌免疫力分化集群 8+ T 细胞分化集群肝细胞癌是肝细胞癌.不可逆的电穿孔是不可逆的编程细胞死亡蛋白1封锁

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