为高血压药物开发决策支持算法,用于数字治疗系统
Jeannie K Lee1, J Skye Nicholas1, Amani Albadawi1
1Department of Pharmacy Practice & Science, The University of Arizona R. Ken Coit College of Pharmacy, Tucson, AZ, United States.
Frontiers in drug safety and regulation
|September 22, 2025
概括
老年人现在可以使用新的数字工具安全地管理错过的高血压药物. 药物教育,决策支持,提醒和监测 (MEDSReM©) 系统为服用逾期剂量提供了一个安全的窗口,提高了药物坚持.
科学领域:
- 老年学是一门学科.
- 数字健康数字健康
- 药理学 药理学是指药理学的学科.
背景情况:
- 坚持高血压药物治疗对老年人来说是一个重大挑战.
- 关于管理遗漏剂量的指导意见有限,导致潜在的不遵守或过量服用的恐惧.
研究的目的:
- 在数字治疗系统中开发和实施用于错过高血压药物的决策支持算法.
- 为了促进老年人高血压和血压的自我管理.
主要方法:
- 对临床,药理动力学和药理动力学研究的文献审查为算法开发提供了信息.
- 该算法经过同行评审,并集成到药物教育,决策支持,提醒和监测 (MEDSReM©) 系统中.
- 使用案例场景将算法编码到移动应用程序中.
主要成果:
- 在MEDSReM©系统包括117种高血压药物和组合产品.
- 对于每种药物,都提供了一个编程的"安全窗口",用于服用遗漏或逾期药物.
- 该应用程序提供"服用,休息和跳过"选项,并提供安全窗口之外服用剂量的指导.
结论:
- 该MEDSReM©决策支持算法提供了一个新的,以老年人为中心的干预,用于管理错过的高血压药物剂量.
- 这种特定时间的数字疗法支持知情决策,可能改善药物守和减少与药物相关的焦虑.
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