一个额外节点的Rosai-Dorfman疾病的案例
Abir Islam1, James P Smith2, Gowrish Vaka3
1Internal Medicine, Edward Via College of Osteopathic Medicine, Monroe, USA.
Cureus
|September 22, 2025
概括
罗莎-多夫曼病 (RDD) 是一种罕见的疾病,可以模仿癌症. 这份病例报告强调了RDD的不寻常的皮肤表现,强调需要准确的诊断来区分它和恶性瘤.
科学领域:
- 病理学 病理学 病理学
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
背景情况:
- 罗莎-多夫曼病 (RDD) 是一种罕见的良性疾病,常常出现在淋巴结中.
- 它的各种临床表现可以模仿更严重的疾病,如癌症,导致诊断挑战.
- 对RDD亚型缺乏临床算法使管理复杂化.
研究的目的:
- 报告一种异常的节点外皮肤性罗莎-多夫曼病病例.
- 强调在软组织质量的差异诊断中考虑RDD的重要性.
- 突出说明组织病理学检查和免疫组织化学如何帮助诊断.
主要方法:
- 一个50岁的女性病例报告,她患有长期存在的,迅速扩大的软组织质量.
- 诊断成像 (CT扫描) 和用免疫组织化学的组织病理学检查.
- 手术切除的质量. 的手术切除.
主要成果:
- 左侧的皮质块最初被怀疑是脂瘤.
- 活检证实了额外节点皮肤罗莎-多夫曼病.
- 手术切除导致症状消失.
结论:
- 这一案例说明了RDD在淋巴结之外的罕见表现,特别是在皮肤中.
- 准确的诊断对于将RDD与脂瘤或淋巴瘤等恶性瘤区分开来至关重要.
- 了解RDD的各种表现可以改善临床管理.
相关概念视频
Rous Sarcoma Virus (RSV) and Cancer
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Rous Sarcoma Virus (RSV) and Cancer
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...


