一个临床病理学研究的H. pylori和消化不良之间的相关性:一个横截面研究
Sushant Nair1, Nitin Wasnik1, Sagarika S Bhole1
1General Surgery, NKP Salve Institute of Medical Sciences, Nagpur, IND.
Cureus
|September 22, 2025
概括
仅仅是消化不良症状在印度对诊断Helicobacter pylori感染是不可靠的. 内镜和组织病理学评估对于准确诊断和有效管理与H. pylori相关的胃肠道问题至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 诊断医学 诊断医学 诊断医学
背景情况:
- 消化不良是印度普遍存在的胃肠道疾病,经常与Helicobacter pylori感染有关.
- 仅仅临床症状通常不足以在消化不良患者中准确诊断H. pylori.
- 需要采用综合诊断方法,整合临床,内镜和组织病理学数据.
研究的目的:
- 评估印度人口中H. pylori感染和消化不良之间的关联.
- 在消化不良患者中评估与H. pylori相关的胃肠病理.
- 为了确定临床症状与内镜和组织病理学发现的诊断效用.
主要方法:
- 一项涉及印度中部92名消化不良成年患者的横截面研究.
- 上部胃肠道内镜和快速尿素酶试验 (RUT) 检测H. pylori.
- 组织病理学分析活检和对H. pylori阳性和阴性组之间的发现进行比较.
主要成果:
- 在47.8%的患者中通过RUT检测到Helicobacter pylori感染.
- 腹膜疼痛是最常见的症状 (76.1%),但与H. pylori状态没有显著的关联.
- 胃炎 (72.8%) 是最常见的内镜发现;胃与H. pylori阳性显著相关 (p=0.0368).
- 组织病理学显示,12%的RUT阳性患者有慢性炎症 (p=0.0346).
结论:
- 临床症状在预测印度消化不良患者中H. pylori感染的价值有限.
- 建议对消化不良进行常规内镜和组织病理学评估.
- 针对特定区域的数据对于制定针对性诊断和治疗策略来治疗腹是必不可少的.
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