由于长期使用双酸盐而导致的非典型股骨骨折:一个病例报告
Madhumati Mandal1, Haiqah Amjad1, Japheth Oyovwi2
1Internal Medicine, Stockport NHS Foundation Trust, Stockport, GBR.
Cureus
|September 22, 2025
概括
非典型的股骨骨折 (AFF) 是长期使用双酸盐 (BP) 的罕见但严重并发症. 对于接受高血压治疗的老年患者来说,早期识别和多学科管理至关重要,以防止并发症.
科学领域:
- 整形外科 整形外科 整形外科
- 药理学 药理学是指药理学的学科.
- 放射学 放射学是一门学科.
背景情况:
- 非典型的股骨骨折 (AFFs) 是不常见的,但与长期双酸盐 (BP) 治疗相关的严重不良事件.
- 双酸盐广泛用于骨质疏松症和其他与骨相关的疾病,有效降低骨折风险,但可能会在长时间使用时抑制骨重塑.
- 这可能会导致缺陷骨折,特别是在大腿骨的下腔和腹腔区域.
研究的目的:
- 强调在接受长期双酸盐治疗的患者中识别非典型的股骨骨折的重要性.
- 强调需要在老年患者中对AFF的高怀疑指数,长期暴露于BP并出现部疼痛.
- 强调及时诊断和多学科管理的必要性,以获得最佳的患者结果.
主要方法:
- 一个81岁妇女的病例报告,她有多发性骨髓瘤病史和长期使用克罗德酸.
- 临床表现包括跌倒,严重的部疼痛和前兆大腿疼痛.
- 诊断工作包括初始成像,盆腔CT和盆腔MRI,以确认AFF特征.
主要成果:
- 这位患者出现了骨骨折和未移位的非典型骨折.
- 放射学发现证实了AFF的典型特征,包括横断断裂线和皮质加厚.
- 没有发现骨髓瘤复发的证据;患者的血压得到了管理,并且AFF通过内钉治疗.
结论:
- 这一案例强调了临床医生在长期接受双酸盐治疗的患者中保持对AFF的高度怀疑指数的关键需要.
- 早期诊断和干预对于预防与非典型股骨骨折相关的进一步并发症至关重要.
- 对于长期接受双酸盐治疗的老年人来说,患者对AFF症状的认识和全面的,多学科的管理至关重要.
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