与食道相关的心血管异常:一个23年的单一中心经验
Saud AlJadaan1, Nourah Alsabty2, Fahad AlTurki3
1Pediatric Surgery, King Abdullah Specialized Children's Hospital, Riyadh, SAU.
Cureus
|September 22, 2025
概括
先天性心脏病影响超过40%的食道缩患者,特别是那些患有综合症或女性性别的患者. 早期的心脏评估对于管理这些复杂病例至关重要.
科学领域:
- 儿科手术 儿科手术
- 心脏病学 心脏病学
- 医学遗传学 医学遗传学
背景情况:
- 食道 (EA) 是一种罕见的先天性异常,常常与先天性心脏病 (CHD) 一起发生.
- 了解EA心脏异常的范围对于患者管理至关重要.
研究的目的:
- 确定患有食道缩症的患者心脏异常的发生率和特征.
- 为了确定与心脏异常和EA患者的干预相关的因素.
主要方法:
- 从2000年到2023年,87名EA患者在三级中心接受治疗的回顾性评估.
- 分析EA类型,综合征关联,心脏异常,以及对心脏干预的需要.
- 统计分析以确定重要的关联.
主要成果:
- 42.5%的EA患者有显著的心脏异常 (不包括PDA/PFO),ASD和VSD是最常见的.
- 心脏异常在女性和综合征患者中更频繁 (p=0.013,p=0.007).
- 综合征状况与心脏异常增加和干预需要相关.
结论:
- 显著的心脏异常发生在42.5%的EA患者中,需要进行彻底的手术前心脏评估.
- 由于心脏异常和干预的发生率较高,女性和综合性EA患者需要专门的注意.
- 多学科管理对于优化心脏伴随性疾病的EA患者的治疗结果至关重要.
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