一个多重获得的平滑肌肉瘤病例,外观丧
Kaoru Chiba1, Itaru Dekio1, Isami Uno1
1Dermatology, The Jikei University School of Medicine, Tokyo, JPN.
Cureus
|September 22, 2025
概括
本案例研究呈现了一种罕见的成年男性获得的光滑肌肉瘤 (SMH),其特点是多个抑郁的,有色素的病变. 它强调了在成人差异诊断中考虑SMH的重要性.
科学领域:
- 皮肤病学 皮肤病学
- 病理学 病理学 病理学
- 在瘤学瘤学.
背景情况:
- 滑动肌肉瘤 (SMH) 是一种罕见的良性皮肤瘤.
- 通常呈现为单独的先天性病变,最常见的是 lumbosacral 区域.
- 获得的SMH具有多个病变和抑郁的外观是非常罕见的.
研究的目的:
- 报告一种独特的获得光滑肌肉瘤 (SMH) 病例.
- 描述这种罕见表现的临床和组织病理特征.
- 强调将SMH纳入成人色素斑点的差异诊断的重要性.
主要方法:
- 一个40岁的男性的病例报告,他有7年的多色素斑块病史.
- 对干部和四肢的病变进行临床检查.
- 来自背部损伤的活检的基因病理学分析,包括α-平滑肌动蛋白 (α-SMA) 的免疫基因化学.
主要成果:
- 组织病理学揭示了皮肤上部分布不规则的光滑肌肉纤维,对α-SMA阳性.
- 观察到基底色素增多,没有原纤维胀或腺缩.
- 不同的诊断,包括贝克尔神经和帕西尼和皮埃里尼的肌皮肤被排除在外.
结论:
- 该患者被诊断为获得的光滑肌肉哈马托马 (SMH),多个抑郁性病变.
- 由于病变的多样性,没有进行切除;在两年内没有观察到进展.
- 这一案例凸显了在成年人呈现多重色素斑点时识别获得的SMH的需要.
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