ENACT

Yanshan Wang1,2,3, Jordan Hilsman1,2, Chenyu Li1,2,3

  • 1Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, USA.

概括

ENACT NLP工作组在13个地点成功部署了自然语言处理基础设施,使得人们可以访问临床叙述进行翻译研究. 这表明了联合NLP部署的可行性,并强调了解决数据异质性的重要性.

相关概念视频

Automatic Processing and Automatic Social Behavior01:28

Automatic Processing and Automatic Social Behavior

Automatic processing refers to the cognitive operations that occur without conscious intent or awareness, playing a fundamental role in shaping social cognition and behavior. These processes enable individuals to navigate complex social environments efficiently by relying on mental shortcuts and pre-existing knowledge structures known as schemas. One of the most influential mechanisms underlying automatic processing is priming, which subtly activates mental representations through exposure to...
218
Natural and Artificial Concepts01:24

Natural and Artificial Concepts

In psychology, concepts can be divided into two categories: natural and artificial. Natural concepts are formed through direct or indirect experiences. For example, consider the concept of snow. If you live in a place with regular snowfall, such as Essex Junction, Vermont, you know snow through direct experiences. You’ve seen it fall, touched it, shoveled it, and played in it. You recognize its texture, appearance, and even its smell. In contrast, if you live on an island like Saint...
545
Nonsense-mediated mRNA Decay02:27

Nonsense-mediated mRNA Decay

The Upf proteins that carry out nonsense-mediated decay (NMD) are found in all eukaryotic organisms, including humans. Each protein has an individual role, but they need to work in collaboration. Upf1 is an ATP-dependent RNA helicase that unwinds the RNA helix. Because Upf1 can unwind any RNA, Upf2 and Upf3 are required to help Upf1 discriminate between nonsense and normal mRNAs.
Usually, Upf3 binds to an Exon Junction Complex (EJC) at mRNA splice sites. If a ribosome fully translates the mRNA,...
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