肌肉强度,EEG生物标志物和工作记忆作为认知功能在认知障碍老年人的相互作用预测器
Yagang Song1, Shuqi Jia2, Xing Wang2
1Department of Physical Education Teaching, Shanghai Sanda University, Shanghai, China.
Frontiers in aging neuroscience
|September 22, 2025
概括
肌肉强度,特别是握力,直接影响老年人的认知功能. 工作记忆和静止状态EEG部分解释了这种联系,表明了对认知健康的潜在干预措施.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 运动学 运动学
背景情况:
- 老年人认知能力下降是一个重大的公共卫生问题.
- 肌肉力量和神经功能都与认知结果有关.
- 将肌肉力量和神经功能与认知联系在一起的机制尚未完全理解.
研究的目的:
- 调查静止电脑图 (EEG) 和工作记忆在肌肉力量和认知功能之间的关系中的调解作用.
- 在经历认知障碍的老年人中探索这些关系.
主要方法:
- 一项涉及137名认知障碍老年人的横截面研究.
- 通过握力和30秒的椅子站测试来评估肌肉力量.
- 休息状态EEG记录,使用双背任务评估工作记忆,并通过MoCA测量全球认知功能.
- 使用PROCESS宏观进行的调解分析,控制共变量.
主要成果:
- 握力对认知功能有直接的积极影响.
- 工作记忆和休息状态EEG部分介导了握力-认知联系.
- 下肢的强度仅由工作记忆来调解,而不是EEG.
- 该模型占认知结果差异的50.7%.
结论:
- 工作记忆和EEG特征在肌肉力量-认知关系中发挥着不同的调解作用.
- 握力可以作为中央神经系统完整性的生物标志物.
- 研究结果表明,在老年人群中,认知健康干预措施的潜在目标是.
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