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2011-2022年在荷兰使用磁共振成像和部分乳房照射的趋势:基于人口的研究

Y A Civil^1,2, A H Eijkelboom³, A E Veldink³

¹Amsterdam UMC location Vrije Universiteit Amsterdam, Department of Radiation Oncology, Amsterdam, the Netherlands.

Clinical and translational radiation oncology

|September 22, 2025

概括

在荷兰,磁共振成像 (MRI) 使用与部分乳房照射 (PBI) 一起增加,但MRI没有增加PBI率. 磁力共振成像使用与较少的阳性边缘相关,但更多的乳腺切除术.

科学领域:

在瘤学瘤学.
放射学放射学是一门学科.
手术瘤学手术瘤学

背景情况:

部分乳腺照射 (PBI) 是早期乳腺癌全乳腺照射的替代方案.
磁共振成像 (MRI) 越来越多地用于乳腺癌管理.
采用PBI和MRI之间的关系及其对治疗决策的影响需要研究.

研究的目的:

调查2011年至2022年期间在荷兰引入PBI和MRI使用之间的关联.
检查MRI对乳腺癌治疗和患者结局的影响.
分析MRI对PBI资格和手术选择的影响.

主要方法:

一项使用荷兰癌症注册表 (2011-2022) 的回顾性队列研究.
纳入标准:年龄≥50岁的女性患有cT1-2N0M0侵袭性乳腺癌或DCIS,在没有新辅助全身治疗的情况下接受手术.
使用后勤回归分析来评估MRI,PBI和治疗结果之间的关联,并对ASTRO PBI标准进行子组分析.

主要成果:

磁力共振成像使用率从2011年的24%增加到2022年的37%;PBI使用率从2017年的3%增加到2022年的21%.
核磁共振并没有与PBI概率相关 (OR 0.98).
在侵袭性癌症中,MRI与DCIS相关的边际较少 (OR 0.81),但乳腺切除率较高 (OR 1.29). 在符合条件的患者中,MRI使用降低了PBI的可能性 (或0.66对于侵入性,或0.80对于DCIS).

结论:

在荷兰,PBI和MRI的使用量都显著增加.
核磁共振并没有增加PBI利用率,并且在某些情况下降低了PBI的资格.
在没有先前的全身治疗的情况下,MRI通过减少特定早期乳腺癌患者的参与边际来提高手术精度.

关键词:

侵袭性乳腺癌是一种侵袭性乳腺癌.这就是为什么MRI是MRI.国家趋势.部分照射乳腺照射

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