韩国患者患有未经治疗的阻塞性睡眠呼吸暂停的抑郁症的患病率和危险因素
Jeongsik Kim1, Hea Ree Park1, Eun Yeon Joo1
1Department of Neurology, Neuroscience Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Frontiers in neurology
|September 22, 2025
概括
抑郁症在患有阻塞性睡眠呼吸暂停 (OSA) 的韩国成年人中很常见,影响24.2%的人. 关键的危险因素包括睡眠碎片化,失眠和白天嗜睡,认知症状最为突出.
科学领域:
- 睡眠医学 睡眠医学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种普遍的睡眠障碍.
- 抑郁症是一种常见的并发症,对生活质量产生重大影响.
- 韩国成年人未经治疗的OSA和抑郁症之间的关系需要进一步调查.
研究的目的:
- 确定新诊断的未经治疗的阻塞性睡眠呼吸暂停 (OSA) 的韩国成年人中临床抑郁症的患病率.
- 确定与此种人群中抑郁症相关的人口,临床和睡眠相关的危险因素.
- 为了探索OSA患者抑郁症的症状结构.
主要方法:
- 评估了887名新诊断患有OSA的韩国成年人的队列.
- 进行了夜间多睡眠测试,并对抑郁症 (BDI-II-K),失眠 (ISI-K),睡眠质量 (PSQI-K) 和白天嗜睡 (ESS-K) 进行了验证问卷调查.
- 使用后勤回归和因子分析来确定风险因素和抑郁症症状模式.
主要成果:
- 在24%的OSA患者中诊断出临床抑郁症.
- 患有抑郁症的OSA患者更有可能是女性,年长,使用安眠药,不太可能炼或就业.
- 更高的兴奋指数,更大的白天嗜睡和严重的失眠是抑郁症的独立风险因素; AHI没有显著意义. 认知症状与抑郁症最为密切相关.
结论:
- 抑郁症在韩国成年人中非常普遍,患有未经治疗的OSA.
- 睡眠碎片化,失眠严重程度和白天嗜睡是OSA患者抑郁症的重要危险因素.
- 对睡眠和情绪障碍的综合管理策略,包括常规抑郁查,建议用于OSA患者.
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