使用FlexNIRS和机器学习在 carotid endarterectomy期间进行非侵入性连续血压预测
Zahra Einalou1, Mehrdad Dadgostar1, Kuan-Cheng Wu1
1Massachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Boston, Massachusetts, United States.
近红外光谱光斑显微镜 (NIRS-PPG) 提供了一种用于连续血压监测的非侵入性方法. 这项研究表明,使用机器学习的NIRS-PPG可以准确地估计平均动脉压,并有可能取代动脉直线.
科学领域:
- 生物医学工程 生物医学工程
- 医疗器械 医疗器械
- 生理监测 生理监测
背景情况:
- 持续监测血压对于患者的稳定至关重要.
- 近红外光谱光斑显微镜 (NIRS-PPG) 是传统动脉线 (A线) 的一种非侵入性的替代方案.
研究的目的:
- 评估可穿戴NIRS-PPG设备 (FlexNIRS) 的有效性,以估计平均动脉压 (MAP).
- 使用NIRS-PPG信号对MAP估计进行线性和高斯过程回归 (GPR) 模型进行比较.
主要方法:
- 从10名患者双边收集NIRS-PPG信号,这些信号是在心动脉内关节切除术期间采集的.
- 开发了特定对象的线性回归和GPR模型,使用NIRS-PPG特征和心率来预测MAP.
- 动脉线读数被用作黄金标准进行比较.
主要成果:
- 所有模型都表现出强的性能,R平方值>= 0.75.
- 一个两种特征的GPR模型实现了0.78的R平方,进一步改进到0.82的第三个特征.
- 在准确度指标 (R平方,MAE,RMSE) 中观察到有统计学意义的改善.
结论:
- 这项初步研究证实了使用NIRS-PPG和机器学习进行非侵入性MAP估计的可行性.
- 在重症监护机构中,NIRS-PPG方法显示为血压监测后A-line移除的切实可行的替代方案.
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