光恐惧症和短暂的单边神经形头痛攻击的解决与结膜注射和撕裂 (SUNCT) 在生长激素腺瘤切除后:阐明拟议的病理生理机制
Ezgi Demirel-Ozbek1, Mustafa Berker2, Isin Unal-Cevik1,3
1Departments of Neurology, Faculty of Medicine, Hacettepe Unıversity, Ankara, Turkiye.
Neuro-ophthalmology (Aeolus Press)
|September 22, 2025
概括
短期单边神经形头痛发作 (SUNCT) 可能是由垂体腺瘤引起的. 通过手术切除了侵袭洞穴鼻腔的复发性垂体腺瘤,完全解决了患者的慢性SUNCT和光恐惧症.
科学领域:
- 神经学 神经学
- 神经外科 神经外科
- 眼科医生 眼科 眼科
背景情况:
- 短暂的单边神经形头痛发作 (SUNCT) 是一种罕见且使人衰弱的头痛疾病.
- 垂体腺瘤可以引起各种神经症状,由于质量效应或荷尔蒙失衡.
- 罕见地报告了SUNCT和垂体腺瘤的同时发生,特别是在洞穴性鼻入侵时.
研究的目的:
- 为了研究复发性垂体腺瘤与洞穴性鼻侵袭和慢性SUNCT与光恐惧症之间的潜在因果关系.
- 为了评估手术瘤切除在解决SUNCT症状中的有效性.
- 在这个背景下讨论头痛和光恐惧症的拟议病理生理学.
主要方法:
- 一个病人的病例介绍,病史有2年的慢性SUNCT和光恐惧症.
- 审查过去的医疗记录,包括壮病,垂体腺瘤切除,以及洞穴性鼻侵袭的复发.
- 对药物治疗,神经阻塞和随后的内镜内性跨状瘤切除的治疗反应的评估.
主要成果:
- 患者经历了慢性,致残的SUNCT和光恐惧症,对初始治疗不耐药.
- 在对复发性垂体腺瘤进行了内镜内性跨形切除后,该腺瘤侵入左洞腔鼻腔,SUNCT攻击完全停止.
- 完整的瘤切除导致ipsilateral头痛和光恐惧症的解决.
结论:
- 复发性垂体腺瘤与洞穴鼻的持续入侵可能是SUNCT的次要原因.
- 潜在的垂体腺瘤的手术治疗可以有效地治疗相关的SUNCT症状.
- 调查和解决二次原因,如垂体腺瘤,对于管理SUNCT患者至关重要.
相关概念视频
Angle Closure Glaucoma: Treatment
1.2K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.2K
Glaucoma: Overview
1.3K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.3K
Open Angle Glaucoma: Treatment
963
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
963


