在心脏和肺移植接受者的捐赠者衍生的感染
Bradley J Gardiner1,2, Michael G Ison3
1Department of Infectious Disease, Alfred Health, Melbourne, Victoria, Australia.
JHLT open
|September 22, 2025
概括
供体感染对心脏和肺移植接受者来说是一个很大的风险. 本综述涵盖了影响移植结果的既定和新兴病原体.
科学领域:
- 移植 传染病 移植 传染病
- 免疫学 免疫学 免疫学
- 微生物学 微生物学
背景情况:
- 心脏和肺移植对于末期器官疾病至关重要.
- 来自捐赠者的感染带来风险,从预期到意想不到的风险.
- 肺部暴露于环境和完整的微生物群引入了各种各样的病原体.
研究的目的:
- 审查关键的既定和新兴的捐赠者衍生的感染.
- 为突出感染特别重要的心脏和肺移植接受者.
主要方法:
- 关于已确定的和新出现的捐赠源感染的文献综述.
- 分析病原体类型 (细菌,病毒,真菌,寄生虫).
- 专注于对心脏和肺移植接受者的影响.
主要成果:
- 捐赠者的肺部可以容纳各种病原体,包括多药耐药细菌,SARS-CoV-2,菌,真菌菌和菌菌.
- 捐赠者衍生的内心炎,毒素菌和夏加斯病是心脏移植接受者面临的重大风险.
- 了解这些感染对于患者管理至关重要.
结论:
- 源自捐赠者的感染在心脏和肺移植中带来了一系列挑战.
- 新出现的病原体和内心炎等特定风险需要持续保持警.
- 有效的管理策略对于改善移植受体结果至关重要.
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