流行前糖尿病和长期COVID的风险:纵向证据
Yusuff Adebayo Adebisi1, Anas Ali Alhur2,3, Najim Z Alshahrani4
1College of Social Sciences, University of Glasgow, 40 Bute Gardens, Glasgow, G12 8RT United Kingdom.
在大流行之前,糖尿病患者面临的长期COVID的风险明显更高. 这一发现凸显了在长期COVID护理策略中为糖尿病患者提供有针对性的支持的需要.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 长期的COVID带来了各种风险因素的重大公共卫生挑战.
- 了解增加长期COVID易感性的预先存在的疾病对于有效管理至关重要.
研究的目的:
- 调查疫情前糖尿病与患长期COVID的风险之间的关联.
- 为了确定糖尿病是否是英国人口中长期COVID的独立风险因素.
主要方法:
- 来自英国家庭纵向研究 (2018-2023) 的11669名英国成年人的前性队列分析.
- 暴露:在2019年之前诊断的流行前糖尿病.
- 结果:长期COVID被定义为持续超过12周的COVID-19感染后症状.
- 使用修改Poisson回归来估计相对风险的统计分析.
主要成果:
- 9.2%的参与者报告了长期COVID.
- 流行前糖尿病与长期COVID (未调整) 风险增加36%有关.
- 在对多种因素进行完全调整后,糖尿病仍然是一个独立的风险因素,长期COVID风险增加了60% (RR=1.60).
- 对于糖尿病患者来说,长期COVID的调整后概率为14.4%,对于没有糖尿病患者来说为9.0%.
结论:
- 流行前糖尿病是长期COVID的独立风险因素.
- 糖尿病患者需要在长期COVID护理策略中加强监测和有针对性的支持.
- 研究结果强调了在流行病后的健康背景下管理糖尿病的重要性.
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